Finally, as FIH (and not the PHDs) is a member of the large JmjC subfamily of dioxygenases, it will be of interest to determine whether comparable sensitivity to H2O2 is shared by these enzymes and affects other biological functions, such as epigenetic regulation.
Overall, it was shown that the planar-YES can be used for the investigation of surface water samples with comparable sensitivity to other reporter gene assays.
Shortening the exposure duration down to 1 3 h and observing the 48 h post-exposure immobility of daphnids in pure medium offered an acute toxicity test setup that reduced the transformation of nanoparticles during incubation, with comparable sensitivity to disclosing toxicity for Ag nanoparticles and CuO nanoparticles.
Considering the TGI concentrations, MDA-MB-231 and SKBR-3 expressing low levels and high levels of both isoforms, respectively, exhibited comparable sensitivity to xanafide.
To reach a comparable sensitivity to the 79.5% of Xpert for microbiologically confirmed TB, MGIT and MODS both required around 20 days.
There are other reports of comparable sensitivity for both IGRA test formats in cases [ 24, 25].
Our results are similar to others which have shown that the rapid NS1 antigen detection test is of comparable sensitivity and specificity to the NS1 antigen capture ELISA [ 14].
Our analysis indicated that testing of combined NTS should yield comparable sensitivities to NPAs for detection of all respiratory viruses of our panel, and is likely to significantly improve the detection of enteroviruses (McNemar's test p = 0.001).
Nasopharyngeal aspirates and throat and nose swabs appear to be of comparable sensitivity (30% and 28%, respectively), while stool specimens are less useful specimens in the first 5 days of illness (sensitivity 20%).
Combining the results of nasal and throat swabs rendered comparable sensitivities to NPAs for detection of all respiratory viruses of our panel and increased sensitivity for enteroviruses.
It cannot be excluded that terrestrial tests are of comparable sensitivity or even more sensitive than aquatic tests as differences in the exposure concentration of the investigated ENMs between soil and aquatic tests are expected.
