Sentence examples for of combinatorial therapy from inspiring English sources

Finally, we discuss novel and feasible approaches that can facilitate the optimal design of combinatorial therapy.

To compare the effects of combinatorial therapy with low-dose arginine and a nitrogen scavenging agent (sodium phenylbutyrate) vs. monotherapy with high-dose arginine on liver function tests in patients with argininosuccinic aciduria (ASA).

On the basis of these screens, selected drug candidates could be identified for experimental validation of combinatorial therapy.

These findings clearly demonstrate the efficacy of combinatorial therapy using sulfonylurea such as gliclazide and teneligliptin in patients with type 2 diabetes.

Our data therefore support the concept of EGFR resistance mediated through induced IGF1R signalling supporting the need for further enquiry regarding the potential utility of combinatorial therapy.

Thus, the PTEN level may serve as a predictive marker for endocrine therapy and may also guide the design of combinatorial therapy.

The manageable safety profile of PD-1/PD-L1 blocking drugs identifies them as suitable for outpatient administration and the development of combinatorial therapies.

The potential for cardiotoxicity is a major consideration in the design and development of combinatorial therapies incorporating anthracyclines and agents that target the HER2-mediated signaling pathway, such as trastuzumab.

These findings are a promising prerequisite for the use of combinatorial therapies in managing TSCI.

Thus, prognosis-guided synergistic gene-gene interaction networks could serve as an efficient in silico tool for pre-clinical drug prioritization and rational design of combinatorial therapies.

Statistical and systems biology methodologies have been proposed for the rational discovery of combinatorial therapies [ 2].