The approach was used for modeling of combinatorial evolution in several applications: (1) DSS COMBI for multicriteria ranking, (2) electronic equipment for image processing, (3) standard for transmission of multimedia information (MPEG, MPEG 2, MPEG 4), and (4) ZigBee communication protocol for wireless sensor network.
Just as new technology paradigms can renew a thesis, one thesis can be merged with another to create a new one in a kind of combinatorial evolution.
The basic result of this combinatorial evolution is that more and more complex computational blocks (indicated as XOR, EQUIV, IMPLY, etc).
The paper describes combinatorial evolution of composite systems.
There seems to be a role for exon shuffling in the combinatorial evolution of animal multidomain, extracellular proteins but this is, obviously, a late, animal-specific development that cannot provide any support for introns-early [ 32- 34].
In technology studies, one of the most accepted definitions of evolution is Joseph Schumpeter's combinatorial evolution (Schumpeter 1961).
Nguyen, R., Allouche, L., Buhler, E. & Giuseppone, N. Dynamic combinatorial evolution within self-replicating supramolecular assemblies.
Combinatorial evolution is another important model to be considered in the evolutionary theory of development.
Finally, we examine recent developments in advanced topics such as utilization of existing tests, test case prioritization, fault localization, and evolution of combinatorial models.
Recent work provides a dynamic view of post-translational histone modifications during differentiation; however there is little insight on the evolution of combinatorial genome-wide patterns of chromatin marks, excluding an essential aspect of developmental gene regulation.
Other regulons share a conserved overall strategy but include additional regulator components to integrate additional regulatory signals, or show transfer of regulation from one regulator to another, or rewiring via evolution of combinatorial interactions between transcription factors [ 36- 38].
