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However, measurement of clinical response at an earlier time point is clinically intuitive.
We also hypothesize that the three psychological factors are moderators of clinical response.
These early changes precede evidence of clinical response but do not predict for it.
Our aim is to delineate transdiagnostic risk factors and biomarkers of clinical response that may inform the pathogenesis of risk and treatment innovation.
IRF5 and STAT6 were decreased, and PPARG was increased, independent of clinical response, and may represent a skew toward a PPARG-driven M2-like phenotype.
This study explores whether inflammatory biomarkers act as moderators of clinical response to omega-3 (n-3) fatty acids in subjects with Major Depressive Disorder (MDD).
For example, Zhu et al. reported a lack of clinical response in pomalidomide-treated patients with relapsed/refractory MM who exhibited the lowest quartile range of IKZF1 RNA expression in their MM cells.
Evidence from recent trials supports early measurement of clinical response.
There were no strong predictors of clinical response.
Introduction Early detection of clinical response is determinants of clinical outcome in people with acute illness.
Preliminary data does not support the hypothesis that a reduction in [18F]FMISO uptake is predictive of clinical response.
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