Sentence examples for of bioactive sequences from inspiring English sources

Towards the goal of biomaterial designs that enable the temporal presentation of bioactive sequences, recombinant bacterial collagens such as Streptococcal collagen-like 2 (Scl2) proteins can be employed to incorporate multiple specific bioactive and biodegradable peptide motifs into a single construct.

Their biological activity can be modified by the inclusion of bioactive sequences, such as cell adhesion motifs.

Herein, we report three new MDP sequences and examine how the incorporation of bioactive sequences and the modification of the hydrophilic amino acids affect cell morphology and cell number over time.

We have shown that the MDP design is flexible and can tolerate a substitution in the hydrophilic face as well as the addition of multiple bioactive sequences.

Furthermore, the effect of processing and in vitro or in vivo digestion on the release and availability of peptides with bioactive sequences is evaluated.

A number of laminin-derived short bioactive sequences, such as Isoleucyl-lysyl-valyl-alanyl-valine (IKVAV), YIGSR, and RNIAEIIKDI, function to encourage cell attachment and growth 27– 29 and synthetic biomaterials are being designed to integrate bioactive ligands within hydrogel scaffolds for promoting cell response, and assimilation within the matrix.

The incorporation of this bioactive sequence is useful for future in vivo experiments where we want to ensure that complete proteolysis of the material is possible.

Our results suggest that threonine-based scaffolds present a more selective matrix for cell adhesion and expansion, while serine-based scaffolds more ubiquitously promote cell expansion, regardless of the bioactive sequence.

Previously we reported the design of ELP hydrogels with selective bioactive sequences interspersed within the elastin-like repeats to enable tailored rates of enzymatic degradation and cell adhesion interactions to better mimic the extracellular microenvironment.

This article describes recent developments in this field, particularly developments over the last two years relating to the grafting of bioactive peptide sequences into the cyclic cystine knot framework of cyclotides to stabilize the sequences.

This study examined the internalization of cyclotides into mammalian cells, a vital step for the delivery of bioactive peptide sequences to intracellular targets.