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One Direction have been a boyband of atypical design, thrown together arbitrarily in a reality show instead of precisely generated in a laboratory somewhere in Orlando or Manchester.
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Despite high grade histology, this group of H3.3 wild-type patients did not follow the expected clinical course of what can be considered classic for children with DIPG, suggesting a potentially different clinical and molecular entity which should be added to the group of "atypical" DIPG when considering clinical trial design.
Using a more stringent controlled design, this study replicated and specified previous findings of atypical brain activation in ADHD during motor response inhibition.
ROCKs and GRKs share a number of atypical features among AGC kinases that may avail them to the design of selective drugs.
KVG performed all analyses, designed and coordinated the study, suggested the causes of atypical amino acid replacements.
Few studies examined the effect of atypical antipsychotics in comparison with a medication-free period using a within-subject design (Hagger et al, 1993; Potkin et al, 2001; Serper and Chou, 1997; Zahn et al, 1994).
Although much more research is necessary, particularly utilizing longitudinal designs, this study provides preliminary head-to-head evidence of atypical antipsychotics.
A high-throughput DNA test will be essential for identifying carriers needed for future studies designed to test the influence of Prnp K211 on development of atypical BSE.
The use of atypical mycobacteria as hosts for the production of M. tuberculosis antigens needs to be designed with the same precautions as for BCG.
Study Design: Cervigrams were obtained from 3134 women with a referral Papanicolaou smear diagnosis of atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion.
However, through a close inspection of two recently-erected statues of atypical appearance, we argue that where the balance of project ownership departs from the norm, a greater degree of design innovation may occur.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com