Sentence examples for of appropriate endpoints from inspiring English sources

In the study of EDCs, endocrinologists and environmental health scientists have proposed a series of criteria that should be met to consider a study "high quality" including the use of appropriate negative and positive controls, the use of sensitive animal species and strains, and the use of appropriate endpoints [ 3, 15- 18].

Translating preclinical data to the clinic requires appropriate selection of representative models, recognition of intrinsic limitations for each model, and selection of the appropriate endpoints to identify effective therapeutic regimens.

Because clinical trial research evaluates therapies aimed at preventing or slowing AD and assesses the benefits and risks of these potential treatments, improved clinical trial design, including the incorporation of more appropriate endpoints to reduce sample sizes and study duration, is imperative8.

Accordingly, the German Advisory Council on the Assessment of Developments in the Health Care System (Sachverständigenrat) recommended in its 2007 report to consider scientific methods for selection of the appropriate endpoints [ 22].

Key issues for the design of clinical trials of neuroprotective therapies include identifying appropriate endpoints and determining the ideal timing of the intervention.

The importance of selecting appropriate endpoint measures that are most reflective of overall surface thrombogenicity is the focus of this review.

Food can serve in a context of prevention, treatment, palliative care, etc., and this will inform the development of an appropriate endpoint model and condition the items to be measured.

The development of shared decision-making tools, as well as appropriate endpoints or outcomes of such tools, should be considered to address communication challenges that may arise from the release of new guidelines.

These parameters are difficult or impossible to control well even in prospective studies due to the overriding concern for patient safety and lack of evidence for the most appropriate endpoints.

The results of the psychometric analyses conducted confirm that these patient-reported measures are appropriate endpoints in clinical trials of psoriasis and that they relate well to the clinical endpoints of PASI, OLS and PGA.

Regulatory guidance documents stress the value of assessing multiple tissues and the most appropriate endpoints when evaluating chemicals for in vivo genotoxic potential.