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The secondary outcome measures will include: the sustainability of prescribed therapy over time, i.e., changes to antithrombotic therapy made during patient follow-up up to 12 months; incidence of any clotting (thromboembolism, stroke) events up to 12 months; incidence of any bleeding (minor or major hemorrhage) events up to 12 months.
Take note of any bleeding.
Rates of any bleeding and major bleeding were similar between the study arms in both RE-COVER (Figure 2B) and RE-COVER II [20, 21].
Fig. 4 a Correlation of any thromboembolic event (n) and the minimal aPTT value (s) and b correlation of any bleeding event (n) and the maximal aPTT value (s) in ARDS patients undergoing extracorporeal lung support with either argatroban or heparin as anticoagulant (solid circle = argatroban; open square = heparin).
Subsequently, the extent of any bleeding is immediately assessed.
The incidence of any bleeding on treatment did not differ significantly between the groups (P = 0.25).
Similar(41)
In atrial fibrillation patients, however, from the RE-LY trial, concomitant intake of clopidogrel and dabigatran etexilate led to an increased rate of major and any bleeding [ 24].
If you cut too far and hit a blood vessel, apply styptic powder or corn starch with a bit of pressure to stop any bleeding.
The frequencies of serious bleeding events and any bleeding events in ADDRESS were also compared between the ≤2 and ≥3 subgroups (Table 4).
There was no advantage of bivalirudin for any bleeding or ischemic endpoints in this prematurely terminated, underpowered trial.
The rates of all bleeding events (any grade) in patients on TA were assessed in studies 2 and 3 (Table 2).
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