Sentence examples for of advanced bladder from inspiring English sources
The prognosis of advanced bladder cancer is generally poor [22].
Treatment of advanced bladder cancer continues to be challenging.
Immune-modulating drugs have recently been introduced to the second-line setting of advanced bladder cancer.
The generally poor prognosis of advanced bladder cancer indicates the need for new therapeutic modalities.
In conclusion, our results have highlighted the potential clinical role of CTC detection as an indicator of advanced bladder cancer.
Eight of these are in 104 muscle-invasive tumour samples included in the TCGA study of advanced bladder cancer (http://cancergenome.nih.gov/cancersselected/invasiveurothelialbladder), and three in muscle-invasive or superficially invasive tumours from the study of Gui et al. (6).
The combination of methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) has dominated the landscape of chemotherapy for advanced bladder cancer for over 15 years.
The combination regimen including methotrexate, vinblastine, doxorubicin and cisplatin (M-VAC) was devised at Memorial Sloan-Kettering in the mid 1980s (Sternberg et al, 1988) and improved overall survival to a median slightly in excess of 12 months and became the standard of care worldwide for advanced bladder cancer (Culine, 2002).
Despite not fulfilling criteria for being a perioperative specific study, we selected a trial of interferon-alpha for advanced bladder cancer at M.D. Anderson Cancer Center.
Representative examples of positive and negative staining of conventional advanced bladder carcinoma are shown in Figure 7A and B. Regarding the distribution of MTUS1 expression within different histopathological subtypes (divided into common urothelial carcinoma (UC), plasmocytoid UC (PUC) and micropapillary UC), a significant expression difference was found (p = 0.011).
In immunohistochemical analysis we found that MTUS1 expression was lost in 50.6% of all papillary and in 45.8% of all advanced bladder tumours.
