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Warning of a "very challenging" 2009, Hans Wijers, chief executive, insisted that the group's fundamentals remained sound and it could meet its refinancing needs.
He's made the best of a very challenging situation.
We stand on the threshold of a very challenging but very exciting future.
"We've been able to deliver for the first nine months of a very challenging operating environment," Coca-Cola's chief executive, Muhtar Kent, said in an interview.
Our growth would not have happened without our really strong board and very good people around me who helped find our way out of a very challenging period.
The UNCHR report concludes: "All these developments take place in the context of a very challenging protection environment for refugees in the region.
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Rajasekhar Balasubramanian, an environmental engineer from the National University of Singapore, told The Associated Press that the "preliminary study" had faced a "very challenging" task of parsing through a lot of complex data. .
"Instead, it is the outcry of a very challenged young man talking about challenges in his life that led him to this point," the interim chief added.
For example, if there are a couple of very challenging vocabulary words that you think may stump your student, you might want to provide a gloss (synonym) for them beneath the passage.
However, gp120 uses many decoys to evade immune surveillance in humans, rendering the development of a protective vaccine very challenging.
Although current computational docking protocols are able to generate near-native solutions in a reasonable time, the problem of identifying near-native conformations from a pool of solutions remains very challenging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com