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Studies may also focus on quantifying the incremental or added predictive value of a specific predictor (for example, newly discovered) to a prediction model.
Studies may also focus on quantifying the incremental or added predictive value of a specific predictor (e.g., newly discovered) to a prediction model (Steyerberg et al, 2012).
Sauerbrei and Schumacher used bootstrap sampling to assess the distribution of an indicator variable denoting the inclusion of a specific predictor for identifying strong and weak factors for predicting survival [ 26].
It is given as, Logit = ln p 1 − p = β 0 + β 1 X 1 + ⋯ + β i X i Where 'p' is the probability of the disease, β0 is the constant and βi is the coefficient of a specific predictor Xi.
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In our opinion, these factors impair the use and generalisability of this marker as a specific predictor of survival in patient cohorts.
However, a previous high-risk offspring study concluded that behavioral disorders are not a specific predictor of BPD; rather the risk of having this condition seems to be elevated among subgroups of offspring with parents with BPD who did not respond to lithium [ 27, 40, 65].
On the contrary, some studies, that retrospectively assessed the sensitivity and specificity of this indictor, concluded that maternal weight gain alone is neither a sensitive nor a specific predictor of poor pregnancy outcomes [ 3].
However, an increased plasma cell-free DNA concentration is neither a sensitive nor a specific predictor of death.
However, whether ERCC1 is simply a generic prognostic factor or a specific predictor of cisplatin efficacy is still to be demonstrated.
When analyses were performed according to PAD status, infection emerged as a specific predictor of non-healing in PAD patients only.
Furthermore it might be important to evaluate what makes a physician think whether a patient has pertussis, considering the fact that our study and other studies show that paroxysmal cough is not a specific predictor of pertussis [ 4, 8, 19].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com