There were delays of up to 45 minutes at London Bridge station because of a signalling problem.
Our hero, Reading-to-London, challenges other trains to races, only to be told he must wait for an hour because of a signalling fault at Twyford.
So, in order to remove these obstacles through the European rail network, the European Commission encouraged the development of a signalling and management system common to all member states: the ERTMS system (European Rail Traffic Management System).
Studies have shown that birds often pay attention to some parts of a signalling pattern and disregard others, which could be of importance in Batesian mimicry, where a palatable species copies the visual appearance of a distasteful model in order to deceive predators.
On the other hand, recycling of the receptors allows the re-stimulation of a signalling pathway.
The ein2 mutation conveys a systemic ethylene resistance through the elimination of a signalling relay step between the cytoplasm and the nucleus [45].
The observed effects could be due to a coupled expression of a DHPR-regulating protein to dystrophin expression, or by the effects of a signalling cascade.
Bub1p is relatively stably associated with kinetochores, and is sufficient to recruit other checkpoint proteins, and therefore displays the two key characteristics of a signalling scaffold.
Therefore, upon activation of a signalling pathway, phosphorylation of YB1 would be an efficient mechanism to modulate local translation of Stau2-bound mRNAs in neurons.
Once activated, ZAP-70 phosphorylates multiple tyrosine residues on the adaptor protein LAT, resulting in the assembly of a signalling complex which includes PLCγ1, Grb2/SOS, GADS and SLP-76 [6].
Such a mechanism would imply that the rate of root growth is at least partially a function of local soil conditions [2] and/or that the C N status of roots is part of a signalling network that regulates biomass partitioning in plants [7].
