Sentence examples similar to of a schedule dependent from inspiring English sources

The non-overlapping toxicity profile of paclitaxel and infusional 5-FU, and the observation of a schedule-dependent synergism between paclitaxel and 5-FU in human gastric cancer cells (Yeh et al, 1998), rationalise such a combination to be evaluated in treating advanced gastric cancers.

In conclusion, dFdC altered the radioresponse of the mouse jejunum in a schedule-dependent fashion.

We hypothesized that sorafenib may also boost the efficacy of irradiation on HCC in a schedule-dependent manner.

These findings suggested that sorafenib modulated the radio sensitivity of hepatocellular carcinoma cells in a schedule-dependent manner in vitro.

According to the rate-limited activation of gemcitabine a schedule-dependent antitumor effect of gemcitabine was found in various in vivo model systems in preclinical studies [ 6] suggesting slower infusion rates in the clinical setting.

One of the reasons that could account for the observed differences in tolerability between the two schedules of ifosfamide might be a schedule-dependent drug drug interaction.

Moreover, in vitro studies [ 14- 17] on human cell lines and primary breast cancer cultures have shown a schedule-dependent interaction of the two drugs.

Here we show that there is a schedule-dependent enhancement of cisplatin cytotoxicity by TPZ for cells in vitro that is similar to that seen with transplanted murine tumours.

These results are in agreement with previous data, showing a schedule-dependent synergism of pemetrexed and the EGFR-TKI erlotinib associated with pemetrexed-induced EGFR phosphorylation (Li et al, 2007; Giovannetti et al, 2008).

The above findings altogether suggested that sorafenib exerted a schedule-dependent effect on the sensitivity of hepatocellular carcinoma cells to radiation.

However, a schedule-dependent combined effect, associated with the order of compound treatments, was observed.