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The authors propose that NICE revisits its definition of a responder.
Development of a responder definition will support the interpretation of scale scores.
One may still discuss what the optimal definition of a responder is, but we would favor studies on MOH treatment that aim at ≥50% reduction in headache index from baseline.
The advantage of using good response as a proxy for the diagnosis of the classical manic-depressive type of BD is that the identification of a responder depends primarily on the patient's behavior rather than on the clinician's interpretation of the bipolar subtype in retrospect.
The definition of a "responder" is a person which symptoms of depression has dropped 50% in MADRS-score from baseline to week 20 or 24, and "remitters" are defined as MADRS score < 10 (Hawley et al. 2002) at week 20 or 24.
In the absence of a responder bias more differences between the groups may have been identified.
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Conclusions: Desmopressin melt, compared with tablet, improves the probability of being a responder.
Each patient was categorized as either a responder (cessation of stabbing pain) or non-responder (continuation of stabbing pain) in response to treatment after 2 weeks.
Another is a friend of a first responder who ended up on the cover of Time.
To present a case of a poor responder woman with a rare balanced autosomal translocation.
The Justice Department said that was "in direct contradiction" to what the role of a first responder should be.
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CEO of Professional Science Editing for Scientists @ prosciediting.com