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In one laboratory model of a replicating RNA system, a reverse transcriptase first produces a DNA strand by using a specific ribozyme as a template, and a second DNA polymerase makes multiple copies from the DNA, thereby amplifying the original RNA strand thousands of times as the cycle is repeated.
Thus we have demonstrated that the entry of a replicating oncolytic virus can be mediated through an interaction between a highly clinically relevant single-chain antibody and its target antigen, and we have shown that this interaction enhances in vivo oncolytic activity.
a The circular genome of a replicating Avidian individual.
Because dsRNA molecules are known to form as the replicating intermediate of an RNA virus, the dsRNA form of a replicating RNA virus was initially assumed to be the silencing trigger in early models, predicting production of equal amounts of sense and antisense viral siRNAs in infected host cells.
We therefore explored the potential utility of a replicating Ad26 vector as a candidate HIV-1 vaccine.
For axiom 1, we include all nucleotides that are part of a replicating system - chromosomal, plasmid, viral and so forth.
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The elicitation of an ERAN of the homophonic sequences of Set A replicates results of a previous study [11].
"There has to be a replicating effect of this training.
Our model system consists of a population of replicating RNA sequences, each of length l = 50 nucleotides (nt).
The next step was development of a replicate simulation model of the material circulation system for the Closed Plant Experiment Facility (CPEF) that is a part of CEEF.
The potential limitations of our study are the relatively small sample size and the lack of a replicate population.
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