Sentence examples for of a given tss from inspiring English sources

Since many reports have also used a window that flanks the TSS of known genes [ 16, 17], we have also defined a different window of same size (5 KB) now encompassing 2,5 KB in each side of a given TSS.

Thus, for a given TSS, only a subset of such splices may be annotated.

Next, we determined if there were specific correlations between the level of transcripts at a given TSS and the level of transcripts detectable by qRT-PCR.

Therefore our data provide a minimal estimate of the whole tendency of the polymerase at a given TSS sequence to enter into the reiterative mode and the true incidence of reiterative transcription is likely underestimated.

A gene is termed as uni-directional if no oppositely oriented TSS is found within 10 kb upstream of the given TSS, or if a similarly oriented TSS is found at least 1 kb upstream.

Based on the most current genome annotation, the transcription start site (TSS), initiation codon and predicted TATA box of a given locus were determined.

Altogether, these observations further validate TSS annotations predicted by EuGene-P and give a demonstration of its power to extend the knowledge of a given regulon.

Due to the widespread existence of alternative TSSs for a given gene and the expected preferred distance of LTSM relative to the TSS, we created a transcript-based sequence set from EnsEMBL55, spanning from the TSS to +200 bp downstream.

Data analysis was based on a "nested case control" strategy using a collection of TSS characterized by a given behavior with respect to repression along with control sites sampled from the genome to make inferences about the probability of a TSS to display a given response to repression based on genomic/epigenetic features characterizing its environment.

The complete TSS region [−100,+100] for all TSSs in a given subset is divided in 40 consecutive non-overlapping sections of length 5 nt.

When the performance of TSSvote was tested by a compiled benchmark set of 21 experimentally determined human and mouse miRNA TSSs (Additional file 6: Table S6), TSSvote predicted 52% of these test TSSs within 500 bp and 81% of them within 2500 bp, outperforming all other currently available methods tested (as measured by the number of miRNA TSSs predicted within a given error range; Figure  3B).