Sentence examples for of a deleterious from inspiring English sources

Because of new mutations, the elimination of a deleterious allele is never complete.

But he said more research was needed to make sure any drug formula tested in a clinical trial would "minimize the likelihood of a deleterious effect".

Moreover, the hypothesis of a deleterious effect related to an excessive tidal volume has not been confirmed in our study.

A balance between migration and selection can lead to the maintenance of a deleterious allele in a population, in a manner closely analogous to mutation-selection balance, discussed above.

Nevertheless, in a subgroup of patients, the presence of a deleterious mutation may have phenotypic consequences.

The MutPred tool calculates the probability of a deleterious mutation and corresponding hypothesis of disrupted molecular mechanism.

Obviously the evolved purpose of BAH-1 is not to mediate adherence of a deleterious microbial product.

The prototype of a deleterious type I IFN response during bacterial infection is experimental listeriosis elicited by the gram-positive rod-shaped intracellular bacterium Listeria monocytogenes that was discovered in 1926 (reviewed in [9]).

One potential explanation for this observation is that accumulation of a metabolite was inducing cell death (i.e. growth rate was hindered only after a period of time that allowed accumulation of a deleterious metabolite).

The mutation was not highly conserved along evolution and the predicted structural data did not plead in favour of a deleterious effect of the N263D substitution on the structure of cytochrome b.

Experiments in animals also support the hypothesis of a deleterious effect of fluctuating glucose.