Sentence examples for of a csc from inspiring English sources

Recent evidence indicates the existence of a "CSC niche," a specialized microenvironment that regulates CSC properties and contributes to tumor initiation, growth, and metastasis.

Note that vulnerability index of a CSP is the same for all CSCs and the asset index of a CSC is the same for all CSPs.

Authors proposed that the Warburg effect could permit reprograming the tumor cells of origin, so that they can acquire the cellular state of a CSC, allowing the conversion of non-CSCs into CSCs [ 76].

The numerical and phenotypic discrepancies in CSC can effectively be accommodated by a relatively simple or minimal definition of a CSC, which only requires this cell to have the potential for extensive self-renewal cycles (O'Brien et al. 2010; Fig. 3).

By the end of a CSC day, I could be pretty tired.

A lot of people ask: where do we start?" Delegates tested a sample of a CSC toolkit for designing programmes for adolescent girls, which the consortium is developing with 20 organisations from eight countries and is scheduled to launch in March.

The enhanced expression of a CSC-like phenotype in ascites-derived tumor cells coincided with the activation of the JAK2/STAT3 pathway.

In this study, using tumor cells isolated from the ascites of recurrent ovarian cancer patients we demonstrate that the emergence of a CSC-like phenotype in response to a short-term paclitaxel treatment in vitro coincided with enhanced staining of β-tubulin III and ERCC1, indicative of an acquired resistance to chemotherapy [ 49, 50].

Building upon the data, a model addressing genotypic and phenotypic heterogeneity arises where the non-CSC progeny of a metastasized CSC could potentially convert back to a CSC, complete with any gained genomic differences (genomic heterogeneity).

Therefore, the implications of CD133 as a CSC marker remain controversial.

This effort led to the identification of salinomycin as a CSC inhibitor.