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The optimized π vector can give significant improvement over the likelihood of a alignment.
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Combination of CR1+CR2 led to an alignment of 861 bp.
Thomas MacEntee, a genealogy educator, writer and speaker, said the explosion of interest in genealogy was because of "an alignment of technology planets".
The first step was the construction of an alignment of a comprehensive set of K+-selective channel sequences forming the putative permeation path.
We present an experimental evaluation of an alignment optimization technique implemented in a parallelizing compiler for Matlab scripts.
Ultimately, the quality of an alignment will only be as good as reference alignment, regardless of the algorithm.
An output hit from cmsearch consists of an alignment and a score.
Shannon entropy was used to score the variability at each position of an alignment of HIV-1 circulating sequences [19].
Input for RNAalifold consisted of an alignment of 140 ERRE variant sequences generated using CLUSTALW (http://www.ebi.ac.uk/clustalw/) [71].
If the overall percent identity of an alignment was above 95%, the genome scaffold was assumed to be a hit.
Initially, we generated several variants of an alignment containing the entire set of compounds (Supporting Figure S1).
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