For the OD mapped OMIM mapped records, we first extracted the cited literature (links to PubMed records for the references cited in an OMIM entry) in the OMIM records.
The third oder mapping function is used only for analyzing the reliability of the signal-based models themselves; in the remaining of this article, the raw estimated MOS values have been used for the instrumental derivation of equipment impairment factors, as subjective scores will usually not be available, and thus no corpus effects will occur.
Bottom panels represent color-coded polar maps of retinotopy, and the color-coded OD-map.
In contrast, in GM6001-treated mice, the deprived (contralateral) eye continued to dominate V1, the ODI was not reduced and warm colors still dominated the OD-map.
In contrast, GM6001-treatment rescued the OD-shift, since after MD V1 was activated equally strongly by both eyes, the ODI-histogram shifted to the left and colder colors appeared in the OD-map.
In both control and GM6001-treated mice without MD, V1-activity was dominated by input from the contralateral eye: activity patches after contralateral eye stimulation were darker than after ipsilateral eye stimulation, the average ODI was positive, and warm colors prevailed in the OD-map, illustrating contralateral dominance.
After 7 days of MD, OD-plasticity occurred only in control (C ) but not in GM6001-treated mice (D ): in control mice, both eyes activated V1 rather equally strong, the OD-histogram was shifted to the left (blue arrow in C ), and colder colors appeared in the OD-map.
In both vehicle- (A ) and GM6001-treated PT-lesioned mice without MD (B ), V1 activation was dominated by the contralateral eye: activity patches induced by contralateral eye stimulation were darker than after ipsilateral eye stimulation, the average ODI was positive, and warm colors dominated the OD-map.
(C ) While 7 days of MD did not induce an OD-shift in vehicle-treated PT mice, and deprived (contra) eye patches still dominated V1, a single treatment with GM6001 rescued OD-plasticity in PT mice (D ): both eyes activated V1 about equally strong, the histogram of ODIs shifted to the left (blue arrow) and colder colors appeared in the OD-map.
Slit-lamp examination (OD) showed multiple map lesions on the endothelium along with fresh, fine and medium-sized keratic precipitates (Figure 1C) and an IOP of 50 mmHg.
Here we used two-photon calcium imaging to reveal an alternative arrangement for OD and SF maps in macaque V1; their gradients run parallel but with unique spatial periods, whereby low-SF regions coincide with monocular regions.
