Your English writing platform
Discover LudwigSuggestions(1)
Exact(7)
Moreover, the applications of the mucoadhesive carrier systems for different administration routes such as the oral, nasal, pulmonary and ocular route are discussed.
Over the last decade, our group has designed and developed a delivery platform based on the polysaccharide chitosan, which suits the requirements of the topical ocular route.
Different systems for drug delivery are costumed for the delivery of drug through the ocular route.
Nonionic surfactants enhanced the systemic absorption of melanocyte stimulating hormone via the ocular route in rabbits [ 85].
In addition, subtype H7 viruses can cause conjunctivitis in mammals (40 ), so human contact with H7N9 virus contaminated water could lead to virus inoculation by the ocular route.
Moreover, all doses of rhNGF tested were well tolerated by healthy subjects when administered topically via the ocular route as a single dose (Cohort 1), fractionated single dose (Cohort 2), and multiple fractionated doses over 5 days (Cohort 3).
Similar(53)
New drug substances from early development are often poorly water-soluble, which causes poor bioavailability upon peroral administration and hampers drug administration through other routes such as the parenteral or ocular routes.
Nonhuman primates (NHPs), such as rhesus monkeys (Macaca mulatta) or common marmosets (Callithrix jacchus) inoculated with MERS-CoV via combined intratracheal, intranasal, oral, and ocular routes, develop transient respiratory disease with little or no viremia although lethal disease was observed in a small number of marmosets [1 4].
We modeled replication in humans (respiratory and ocular routes) by inoculating differentiated normal human bronchial epithelial cells (NHBEs) or primary human ocular cells (cornea and trabecular meshwork) with Env/9306 (multiplicity of infection 0.01) (Technical Appendix).
In one room, 54 birds (27 from each line) were infected with 4 lof10 CID50 (10 CID50) of virulent IBV-M41 strain in a total of 100 μl of 0.2 % BSA in PBS equally by intra nasal and ocular routes.
Ducks (n=2/virus group) were infected via natural route (ocular, nasal, and oral) by inoculation with 10 EID50 units of virus in a total volume of 1 mL phosphate-buffered saline (PBS).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com