Sentence examples for ocular expression from inspiring English sources

Finally, the neutralization of IL-17 attenuated ocular expression of CXCL2 and CXCL5, two cytokines which are chemotactic for neutrophils.

Previous studies documented that constitutive ocular expression of FasL maintained immune privilege and prevented neoangeogenesis.

Ocular expression of FasL is thought to be required for the maintenance of immune privilege by limiting ocular inflammation [42] and/or neoangeogenesis [43].

More recent studies, however, reveal an apparent paradox in FasL function within the ocular environment, where ocular expression of membrane-bound FasL actually promotes immunoreactivity.

The data revealed that intravitreous injection of Avastin in rat CNV model, not only inhibited VEGF ocular expression, but also suppressed the mRNA and protein expression of Dll4, as shown in a previous study [38], implying that VEGF acted as the upstream of Dll4 in CNV angiogenesis.

To examine the ocular expression of Hgsnat at different developmental time points, we performed RT PCR analysis of total RNA from mouse eye.

Numbers and quantitation: more detail is needed throughout, e.g. for the phenotypes of 'variable expressivity' (eleventh paragraph) resulting from pan-ocular expression of BMP4.

The pan-ocular expression of BMP4 resulted in a strong response of the reporter, indicating pan-ocular BMP4 signaling.

Macroscopically, the pan-ocular expression of BMP4 results in phenotypes including a 'Plattauge' (flat-eye), in which the ventral part of the eye is strongly affected and a milder phenotype, in which the ventral retina develops, but with a persisting optic fissure.

These observations suggest that the specific down-regulation of vascular endothelial growth factor production is sufficient to reduce the corneal neovascular response and that recombinant adenovirus might be a useful vehicle to produce antisense RNA in situ to down-regulate ocular gene expression.

The most surprising result was the upstream position of Hh signaling in the head because this differs from the Drosophila situation, in which ocular wg expression is unaffected in hh mutants, while the hh stripe is slightly altered in wg mutants (Gallitano-Mendel and Finkelstein, 1997).