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The gene region in which DNA methylation occurs contributes to the complexity of its effects on transcription [ 22].
Consistently, p53L348,350A was also resistant to hemin-accelerated degradation, suggesting that hemin-induced degradation of nuclear p53 protein, if it occurs, contributes little to the hemin-triggered decrease in total cellular p53 protein.
The liver, where synthesis of IGFALS mainly occurs, contributes most of the circulating IGF1, whose stability depends on forming a ternary complex with IGFALS and IGF-binding protein 3 (IGFBaxteraxter & Dai, 1994; Dai & Baxter, 1994; Sjogren et al, 1999).
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Additionally, as a side effect of the first two steps of metabolism, an increase in the blood concentration of lactic acid occurs contributing to lactic acidosis.
While assessing both the impacts of risks and the probability of them occurring contributes to project success (Oehmen et al. 2014; Raz et al. 2002; Salomo et al. 2007; Teller et al. 2014), it has not been investigated how risk assessment is considered in anticipations of project success.
Accretion of crust or sediment may occur, contributing to a net growth of the upper plate, but sedimentary or crustal erosion (also called tectonic erosion) is also possible, resulting in a net loss of upper plate material.
Both polyethylene/PE-induced osteolysis and implant-to-bone or implant-to-implant contact may still occur, contributing to the risk of screw-breakage and resulting long-term failure.
Personal barriers to employment, work disincentives inherent in the SSI and SSDI programs, a fragmented and poorly coordinated system of supports, and limited means by which early intervention might occur contribute to the difficulty facing policy makers in developing the means to reduce disability expenditures.
Encouragingly, scientists from countries where iguanas occur contributed significantly to the compilation.
Due to the construction of the Swedish PBS [ 11], stockpiling can occur, contributing to higher CMA.
In contrast, in TGF β-resistant high-grade tumors, potentiation of UCP2 repression fails to occur, contributing to impaired cell differentiation.
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