Then, too, a complicated medication regimen or the occurrence of side effects may result in noncompliance: the patients simply stop taking the drug or take it less often than prescribed, reducing its therapeutic benefit.
Occurrence of side effects was compared between weeks with McNemar´s test.
The need for rescue analgesia and occurrence of side effects were also recorded in the two groups.
The clinical effect and occurrence of side effects of propofol are generally dose- and time-dependent [10].
The occurrence of side effects or adverse events were also recorded at first and third month of pregabalin intake.
Patients for whom the treatment was stopped because of the occurrence of side effects were not included in the statistical evaluation of heterotopic bone formation.
Rahimtoola et al. [28] found that the main reasons for discontinuing treatment after only one prescription, was inefficacy and/or the occurrence of side effects.
At our institution, over the past few years, the use of intravenous colistin was often associated with occurrence of side effects, mainly nephrotoxicity and neurotoxicity.
There was no relationship between the patients'dosage of pregabalin, or the time of titration, and the occurrence of side effects (data not shown).
Moreover, we injected BTX-A in small doses at multiple sites to reduce the occurrence of side effects as recommended by Ates [7].
Other outcomes that we evaluated were microscopic gametocyte prevalence, treatment efficacy and the occurrence of side effects.
