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Although basing this study on MRF members had a number of pragmatic advantages, our respondents had a much higher occurrence of after-effects than would be expected from a random sample of families affected.
Our data also show a more frequent occurrence of mentor effects after pollination by hexaploid than by tetraploid pollen donors (Table 2).
Analyses were mostly performed 48 h after hypergravity treatment, as a trade-off between the timeframe usually needed to observe effects of treatments on PC12 cell phenotype under differentiating conditions [ 35] and the potential occurrence of recovery effects after hypergravity stimulation [ 36].
The primary outcomes are the occurrence of side effects three and six months after the start of intake of endocrine therapy.
Hence, HIA addresses some (but not all) right-to-health principles in consideration of a project before and after the occurrence of actual effects [ 27].
Clinical studies are also needed to investigate the occurrence of side effects from vasopressors in humans after resuscitation and their possible influence on hospital survival.
Rahimtoola et al. [28] found that the main reasons for discontinuing treatment after only one prescription, was inefficacy and/or the occurrence of side effects.
Use of an oxytocin infusion after an initial bolus did not increase the occurrence of side effects.
We were not able to collect data after microinjection of ATPA into the amygdala due to the occurrence of side effects.
However, as post-chemotherapy samples were obtained 1 2 weeks after the initiation of chemotherapy, this might not suffice for the occurrence of immunosuppressive effects of the chemotherapy.
Thus, our data clearly support the tight safety index of methadone, previously illustrated by the occurrence of significant respiratory effects after intake at pharmacological dosages [ 27].
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