Increasing evidence supports that lncRNAs play a crucial role in disease occurrence, genomic imprinting and developmental regulation in mammals [ 13– 15].
As described, the time-to-event model deals with the timing and occurrence of developmental events: divisions, deaths, final differentiation.
The aim of the present study was to elucidate the developmental occurrence and control of Ser phosphorylation in COS BTPC using a phosphosite-specific antibody.
This study investigated the relationship between early subclinical autistic traits and the occurrence of later developmental and behavioural problems as well as problems in cognitive and language functioning.
However, this mode of propagation is often hampered by the occurrence of developmental aberrations and non-embryogenic callus.
The diagnostic criteria for the disorder are broad distal phalanges of the thumbs and big toes, accompanied by a broad and shortened nose, sensorineural hearing loss and developmental delay, with predominant occurrence in males.
The TFBS classes shared in common by the stress-associated orthologs with other paralogous genes are largely associated with basal growth and developmental functions, ranging in occurrence from a simpler non-modular combinations of five TFBS classes per cluster to a more complex but non-modular combinations of more than ten TFBS classes per cluster.
This study was conducted to examine the relationship between early subclinical autistic traits and the occurrence of later developmental, behavioural, and cognitive problems.
Furthermore, in terms of biological process, genes related to biological regulation and developmental process, mainly involved in the synaptic occurrence, neuronal migration and interaction, were also actively expressed.
Prevalent occurrence of developmental TFBSs regardless of cluster and species may be an indication that extensive binding of developmental TFs on UCEs existed in metazoan ancestors and these TFs regulated various nearby genes to coordinate developmental functions.
