Sentence examples for occurred fourfold from inspiring English sources

Correlating with the higher prescribing frequency of glimepiride, severe hypoglycemia associated with glimepiride occurred fourfold more frequently than severe hypoglycemia associated with glibenclamide (65 vs. 16 episodes; 1 event concerned gliquidone) (5) (Supplementary Fig. 1).

Although boron is usually found in triangular coordination with three oxygens, it also occurs in fourfold coordination in tetrahedral groups.

Wimmer et al. show that malignancy occurs approximately fourfold more frequently in renal-transplant recipients than in a normal control population.

During OT infusion, about a fourfold increase occurred in overall IUP.

If a fourfold increase occurred in antibody titre in the neutralization test or if the ELISA test was seronegative in the first sample and seropositive in the second sample, the calf was considered to have a rise in titre and to be recently infected with the relevant virus.

The analysis of purified enzyme preparations showed that the transfer of allyl groups via the SAM analog allyl-SAH occurs with a fourfold increased kcat of 11 × 10−3 s−1 compared to 3.2 × 10−3 s−1 for methyl transfer.

The greatest ERN and PRN differences occurred with tumor grade: a fourfold greater risk of the tumor being ERN existed if it was grade 3 compared with grade 1 (Table  3).

Choice of normative database and number of skeletal sites considered had a substantial effect on the estimated prevalence of osteoporosis in older men in this study; a fourfold increase in the prevalence occurred when we defined osteoporosis by using NOF (male normative database, three skeletal sites) instead of WHO (female normative database, one skeletal site) criteria.

Although the parametric approach was faster and easier to implement, the Adaptive IBEA identified significantly better configurations in many cases, especially where veering occurred, in one case improving modal loss factors more than fourfold vs the parametric method.

Samples were considered as dengue positive if (1) DENV nucleic acid was detected; (2) DENV NS1 antigen was present; or (3) (i) DENV IgM seroconversion occurred in paired sera, (iii) dengue total antibodies had a fourfold rise in titers in paired sera, or (iv) a combination of the above.

The number of the cells increased immediately following induction of differentiation, expanding fourfold by day 2, suggesting that two cycles of cell division had occurred.