Egg and offspring mortality occur cumulatively throughout the breeding season, therefore in any given year, counts in the middle of winter will be more representative of the breeding population than counts later in the season.
These molecular alterations occur cumulatively in up to 70% of all follicular cell-derived thyroid carcinomas in a nearly mutually exclusive manner [ 6- 9].
The prevailing dogma of cancer evolution is therefore one of "gradualism" in which acquisition of driver mutations occurs cumulatively over years to decades, resulting in incremental progression through increasingly malignant phenotypes (Jones et al., 2008).
It is worth mentioning that there is a close correlation of the time period when vaccine A was brought to market in Europe in 2004, with cases of haemorrhagic diatheses occurring cumulatively in 2007, and it being available for vaccination in New Zealand in May 2008 where also, three years later, the first diagnosed case of BNP occurred in August 2011.
We counted events that occurred before treatment cumulatively for 12 month periods backwards in time up to three years before treatment.
In the real world, the damage that these chemicals are doing is occurring slowly and cumulatively, over years and decades.
The multiple-hit hypothesis of neurotoxicity upon which these studies were based postulates that insults to different target sites within a specific brain system, here the nigrostriatal DA system, when occurring concurrently or cumulatively, will compromise homeostatic and repair capacities of the system and thereby increase its vulnerability.
Another source of uncertainty is whether a net directional rate shift in a clade has occurred in a single large step or cumulatively in several smaller steps along successive branches.
Cumulatively, these observations suggested that no serotype-related antigenic changes occurred in the spirochetes during infection in ticks.
This life history confounds our understanding of the processes affecting population dynamics, because pivotal events may occur during any stage or cumulatively across stages [1].
