Exact(2)
ERK1/2 activation has been shown to occur in a model of adult pancreas regeneration after pancreatectomy [48].
Given the effective blocking by the RSK-inhibitory peptide of molecular pathways leading to liver fibrosis in an acute CCl4 model of liver injury and fibrogenesis, we asked whether these effects would occur in a model of established liver fibrosis due to chronic liver injury, reproducing the disease state of patients with severe liver injury and fibrosis.
Similar(58)
To the best of our knowledge, this is the first study to indentify and monitor SBC as they occur in a preclinical model of OA.
We thus investigated whether bacterial translocation to mesenteric fat and lymph nodes may also occur in an experimental model of ileitis.
Here, we disentangle the energy- and charge-transfer processes occurring in a model system based on blends of cadmium selenide nanocrystals (CdSe-NC) with poly[2-methoxy-5- 3′,7′-dimethyloctyloxy -1,4-phenylene vinylene] (MDMO-poly[2-methoxy-5- 3′,7′-dimethyloctyloxy -1,4-phenylened luminescence measurements.
The observed transient drop in cases observed prior to initiation of the interventions (in Figures 2 and 3) likely represents damped oscillations occurring in the system, as would be expected to occur in a dynamic model with replacement of removed individuals with susceptibles.
The analogy to conventional modeling can be clearly seen in this layer as the reaction rate, the ODE and the conservation relation for the effector could also occur in a conventional model describing the association of two species.
The marked response of the p53-null mammary epithelium to a short-term exposure to hormone raised the question of whether a similar response would occur in a more tumorigenic model of mammary tumorigenesis.
It is not yet clear whether this fitness is sufficient to result in a phenotypic conversion of a tumor in vivo, and it would therefore be interesting to determine whether this occurs in a preclinical model of tumor development.
The health benefits conferred by SRT2104 led us to determine whether short-term treatment could offer protection against disuse atrophy of muscle and bone that occurs in an experimental model of prolonged immobility.
Valvuloseptal deficits also occur in an avian embryo model of TCE exposure (Loeber et al. 1988).
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