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To further investigate the effects of Mn exposure on various systems, we have established a prospective cohort study which includes data on individual Mn exposure and the results of regular occupational examination.
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All doctors must be qualified to carry out occupational health examination, especially, and the examining physician always served these occupational workers in the past years and had sufficient expertise to diagnose manganism or even signs of Parkinsonism.
The occupational health examination was conducted at the same visit.
The Guangzhou Occupational Diseases Prevention and Treatment Center established a regular occupational health examination system to monitor the workers' health and occupational hazards [ 11].
The occupational health examination was performed in the morning at the end of the work shift after overnight fasting.
The HADS questionnaire was given to salaried employees at 19 major French companies as part of their biennial occupational medical examination.
It will be important for Mn exposed workers to control drinking and also assess liver function in the occupational health examination.
According to a population survey conducted in 2006, two out of three employees had attended an occupational health examination in the past three years, and around half of them had had occupational health personnel assessing their workplace in the past three years.
The standardized exam was strictly performed based on those items of general chart of occupational health examination including symptoms, clinical signs, and some special tests like lung function, which were generally required by Chinese law and regulations.
Occupational health examinations were conducted by experienced occupational health physicians and included detailed standardised questionnaires regarding occupational and life style factors, physical and functional exams, and laboratory measurements.
Information on demographic characteristics and smoking status was collected through occupational health examinations in factories and driver examination stations from March 1988 to December 1992.
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