We found that JPHs are evolutionary highly conserved, in particular the membrane occupation and recognition nexus motifs found in all species.
However, as Spanish troops were currently in occupation, this recognition was seen as little more than a gesture to keep Honoré happy.
The membrane occupation and recognition nexus protein 1 (MORN1) is highly conserved among apicomplexan parasites and is associated with several structures that have a role in cell division.
In addition to the centrins, a polo-like kinase, TbPLK1 and a MORN- (Membrane Occupation and Recognition Nexus) containing protein, TbMORN1, were recently identified to be on the bi-lobe [11], [12].
The membrane occupation and recognition nexus protein 1 (MORN1) is highly conserved among apicomplexan parasites and is associated with various structures that have a role in cell division [5], [12].
MORN1 is composed of a short unique N-terminus, 14 membrane occupation and recognition nexus (MORN) repeats, a linker of 5 amino acids between MORN domains 6 and 7 and a C-terminus composed of a 15th but degenerated and partial MORN motif [5].
Membrane Occupation and Recognition Nexus protein (MORN1) seems to be related to cell division in all Apicomplexa studied, and functions in both asexual and sexual reproduction [ 56].
Besides PACRG and SPAG16L, MEIG1 also associates with transcription factor-like 5 protein (TCFL5) (Shi et al., 2013), and membrane occupation and recognition nexus repeat-containing 3 (MORN3) (Zhang et al., 2014).
For example, myeloid differentiation factor 88-5/sterile andha and TIR motif-containing protein 1 (MyD88-5/SARM1) is required for axotomy-induced axon degeneration, and membrane occupation and recognition nexus repeat containing 4 (MORN4) is required for Taxol-induced degeneration.
First, IMC associated proteins, comprises alveolin proteins, a membrane occupation and recognition nexus protein (MORN), which associate with IMC and spindle poles and are indispensible for asexual and sexual development (Ferguson et al., 2008).
