The permeation of OCAs into the intact skin is slow due to the resistance of stratum corneum.
Recent publications have shown decreased infection rates, reduced wound drainage, and improved cosmetic satisfaction when comparing OCA closure, with and without sutures, to skin staples in total hip arthroplasty [3, 11, 12, 13, 14].
Previous work on optical clearing was mainly focused on searching the appropriate and biocompatible optical clearing agents (OCA) or improving the delivery of agents into skin so as to achieve a better optical clearing effect.
Some penetration enhancers can be added in OCAs to improve the delivery of agents in skin so as to achieve a better optical clearing effect.
Recently, several studies have challenged the superiority of metallic skin staples when compared to skin closure with OCA with and without sutures [3, 11, 12, 13].
The genes associated with oculocutaneous albinism (OCA) such as HPS1, HPS3, HPS4, HPS5 and HPS6 were expressed in sheep skin but most of them did not show differential expression associated with coat color.
"I still love tennis," Montes de Oca said.
(His previous store, OCA, in Carmel, Calif., closed in 1968).
Perhaps this is the year to plant oca and yacon.
Oca swung out wide and Nicchio seized his chance.
