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Therefore, strategies combining partial BACE1 suppression with inhibition of the BACE1-elevating pathway (e.g., eIF2α phosphorylation) may be useful for increasing the therapeutic benefits while obviating the potential adverse effects in treating AD and related memory deficits.
Indeed, apoptosis may even be protective, by obviating the potential of injured cells to necrosis and further propagating the inflammatory response.
It is also important to state here that CGHub's use of the BT-using GT is currently in a client/server mode, not in the more common peer-to-peer mode, thus partially obviating the potential performance benefit of a many-to-many transfer scheme (there is still some benefit in being able to scale the server 'peers' controlled by CGHub).
The modular cemented NexGen CR tibial tray was equipped by the supplier with four 1.0-mm tantalum markers encased in titanium rods, attached to the undersurface of the tray and 1 at the tip of the stem, thus obviating the potential risk of movement between the polyethylene and the tray components if markers were used in the polyethylene.
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Whole-genome sequencing is potentially comprehensive and obviates the potential problems associated with selection and incomplete capture of exons, but is substantially more expensive than exome sequencing using current generation parallel sequencing protocols and instrumentation.
Recently, the EU decided that to obviate the potential human rights violation, passengers would be permitted to opt out of the full-body scan in favour of a pat-down search.
This enquiry obviates the potential problem of faulty recall over periods of 3 months [14].
Since the technique obtains measurements in the supine position, it also obviates the potential of creating orthostatic symptoms in the ED environment.
CWU surgery is preferred in children because it obviates the potential requirement for lifelong ear care, improves the fitting of hearing aids when required, and is less likely to lead to otorrhoea associated with swimming [3].
We will present extensive data from human trials documenting the efficacy of the transient upregulation of local blood perfusion during active tissue cooling at the knee as a means to preclude the occurrence of long term ischemia in conjunction with cryotherapy and thereby obviate the potential for NFCI or tissue reperfusion injury.
This obviates the potential problems of subjective coding of data.
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