Sentence examples for obtaining specificity from inspiring English sources

The majority of kinase inhibitors target the ATP-binding site which, due to the conserved nature of this site among kinases, often leads to difficulties obtaining specificity [ 11].

This has been a major limitation to lentiviral introduction of exogenous transgenes, which either quickly become silenced or are not truly expressed in a cell-specific manner, despite numerous attempts to obtain specificity [29 31].

A variety of experimental techniques have been developed to elucidate the peptide specificity for many modular signaling domains and obtain specificity profiles (e.g., the so-called Position-Specific Scoring Matrices, PSSMs), as a quantitative measure of the preference of each kinase domain for each amino acid residue at every peptide substrate position.

The obtained specificity was 82.65 and sensitivity was 83.63.

HuR does not act in isolation and interplay of HuR with other proteins and miRNAs is necessary to obtain specificity of interaction with these mRNAs.

The score ranges from 0 to 7 points, and the cut-off was set at 6 points to obtain specificity >85%.

The obtained specificity for proteoliposomes is subsequently discussed in the context of the two "initial receptor models" and the evolutionary development of the chloroplast translocon.

This strategy is employed nationally in the U.S. and in global HIV surveillance efforts to enhance recall and obtain specificity in recent sexual behaviors of populations most at risk for HIV [ 20].

To achieve sensitivity with such few reads, we started with the set of TIC alignments with an overhang of 8 nt, and used a clustering method to to obtain specificity.

We outline a SEQRS experiment focused on obtaining the specificity of a multi-protein complex between Drosophila RBPs Pumilio (Pum) and Nanos (Nos).

A pictorial representation of a pathway with no cross-regulation obtaining mutual specificity is given in Fig. 2A.