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A 6-week therapy with corticosteroids was prescribed, obtaining remission of visual disturbance and left papilloedema improvement, while headache episodes persisted with a mildly reduced frequency (one to two attacks/day, 4 days/week).
Research has shown that rheumatologists' non-adherence to the EULAR treatment guidelines in fact results in not obtaining remission [ 18].
It was a strong predictor of higher disease activity and thus contributes to failure in obtaining remission.
It was interesting that the OR for obtaining remission was similar between those with higher and lower albuminuria.
Moreover, biologics are at higher risk of severe side effects and are much more expensive than a high-dose probiotic treatment in obtaining remission in relapsing UC.
People may argue that a higher dose of 5-ASA therapy might be just as well tolerated and may be more convenient and less expensive for obtaining remission.
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Johann Tetzel, a Dominican friar locally famous for his zeal in selling indulgences, is said to have boasted that one of the new ones could obtain remission from sin even for someone who had raped the Virgin Mary.
Further research into the potential legal repercussions of failing to obtain remission is needed.
Notably, most cases (82.8%) obtained remission at the 1-year study time point.
The JDDM study also reported that 39 (22.3%) of 136 patients obtained remission over 3.8 years of observation (10).
Following the standard treatment with intense combination chemotherapy, 50 80% of adult patients obtain remission, but the majority ultimately relapses and only 20 30% are cured.
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