One, a very general way, is to obtain margins or edges where physical stimulation reveals differences.
While wider margins of resection increase the likelihood of obtaining negative margins, it comes at an increasing financial, cosmetic and psychological cost to the patient.
Furthermore, obtaining wide margins is not always feasible if a prior excision leaves no residual breast tissue behind.
Application of the linear staple device to the distal rectal tube, for example, presents challenges in obtaining safe margins.
Bleicher and coworkers studied 290 patients with and without MRI and found no significant difference in conversion from BCT to mastectomy or in the likelihood of obtaining negative margins with a single surgical excision [ 6].
Metastases are rarely encountered but because of difficulties in obtaining wide-margin resection of the primary tumour, local recurrences resulting in tissue destruction are common, eventually killing the patient.
Therefore, cost-sensitive margin distribution learning is brought forward to obtain balanced margin distribution and detection rate between two classes.
MATLAB software digital image processing technology was used to obtain outer margin profile from stereomicroscope photograph of the serrated incisors.
Using Monte Carlo simulations, Celestino et al. (2006) obtained the margin of safety of tunnel structure to evaluate the probability of failure according to load and resistance factor design principles for the failure modes.
The best results are obtained with margin 0.1.
