Both in aqueous and in biological solutions we obtained good sensitivity and reproducibility of the SERS signals for the anti-Parkinson drug apomorphine, and for the anti-epilepsy drug carbamazepine.
The method obtains good sensitivity by the optimal design of two different neutron die-away regions: a short die-away for the neutron detector region and a longer die-away for the sample interrogation region.
Third, biological samples containing proteins have high background fluorescence, making it difficult to obtain good sensitivity using simple fluorophores.
Our ROC analysis also indicates that CAPS protein levels needs to be used together with other markers to obtain good sensitivity and specificity to predict outcome.
Weaknesses have been identified with this methodology in modeling disease progression, obtaining good quality information on costs for patients treated in the community, and sensitivity to small changes in estimated incremental costs.
Moreover, despite the sensitivity of 17 toward hydroxide or alkoxide base, the basic nature of the reactions did not hinder us from obtaining good yields of the desired products.
Positive or negative ionization methods were tested and compared to obtain good specificity and sensitivity for yakuchinone A and IS determination.
Some studies have had doubt on the usefulness of sputum Gram stain in terms of difficulty to obtain good quality samples, sensitivity, reliability, and overall impact on treatment decisions [ 1– 3].
When applied to samples from regions with a lower NPC risk than China like Morocco, North Africa (medium risk), its performance decreased, and thus, we tried to modify the assay to obtain good specificity and sensitivity for tumors in such areas.
This afforded us with the opportunity to compare the set of SNPs identified from the pooled sequencing with the set of SNPs determined from the individual sequencing and thereby obtain good estimates of the sensitivity and specificity of our method.
