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In addition to obtaining adherence estimates, participants provided data on reasons for failing to adhere to medication regimens, such as forgetting, not having their medicines with them while traveling, worries regarding side effects, and stigma/confidentiality concerns.
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We obtained adherence status in 302/320 (94%) participants.
In order to obtain adherence to the study, two nurses were allocated to manage implementation of the sedation protocol between the study periods, and facilitate data collection throughout the study.
IMB model-based intervention content might include strategies to ensure patients possess appropriate knowledge about their medication regimen (i.e., dosing schedules and handling missed doses) and skills to obtain adherence information when needed (e.g., to access trustworthy sources and ask providers about medications).
Many studies have focused on the optimal approach for obtaining high adherence and low levels of missin data.
For example, obtaining high adherence in HCWs has not been feasible in some high-income countries such as Australia [ 41].
The convenience and privacy possible through IVR may increase the feasibility of obtaining daily adherence data at the same time that it decreases social desirability bias.
The difference of the two was then divided by 30 before being multiplied by 100 to obtain percentage adherence.
This allowed us to accurately obtain the adherence data, unlike in other studies [ 17] where an active participation of the patient for data collection was expected.
Prior to enrolment, eligible patients were given details of the study and written informed consent was obtained, in adherence to local recruitment laws.
The first author will train all research assistants in how to conduct the data collection in order to obtain protocol adherence.
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