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This increases our confidence that participants were effectively able to engage with the conjoint task, and that the obtained utility values for each subaction were valid.
These values are also relatively similar to those found in a PH study that obtained utility values from the SF-6D [ 20].
We obtained utility values (Table 2) from previous publications and the Cost-Effectiveness Analysis Registry from the Institute for Clinical Research and Health Policy Studies, Tufts Medical Center [ 26- 35].
They obtained utility weights for the states by a linear regression analysis of the correlation between urinary symptoms and EQ-5D scores in a Swedish willingness-to-pay survey [ 7].
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We obtained utilities for long term complications from available literature [ 16].
We obtained utilities for postoperative pain, nausea, vomiting, urinary retention and myalgia from 100 adults prior to elective surgery using SG.
No studies have obtained utilities for a broader set of health states that capture both the intended (clinical response) and unintended (toxicity) effects of available treatments for advanced melanoma.
But, following the U.S. Supreme Court's decision in Alice v. CLS Bank, obtaining utility patent protection for software-related inventions has become more difficult and less predictable.
When people make medical payments, they, of course, do not obtain utility from making the payment itself.
Thus, value is the "comparative appreciation of reciprocal skills or services that are exchanged to obtain utility; value [means] 'value in use'" (Vargo and Lusch 2004, p. 7).
The methodology also considers the flowsheet simulation of each enterprise involved in the EIP in order to obtain utility consumption of each enterprise operating by itself.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com