Exact(6)
We also obtained resistance values of intact ETTs as controls.
We first used verapamil to test whether IEDR clinical isolates obtained resistance phenotype via efflux mechanism.
These data have shown together that IEDR isolates obtained resistance due to the effect of the efflux pumps.
Amongst the MSSA isolates obtained, resistance to penicillin, tetracycline and SXT was common, but not to any other antibiotics – see Table 4.
GLC4-Adr obtained resistance to doxorubicin, but also to a wide range of other chemotherapeutic agents, by stepwise increasing concentrations of doxorubicin (Zijlstra et al, 1987; de Jong et al, 1990; Meijer et al, 1991; Versantvoort et al, 1995).
The fact that we never obtained resistance from treating NYH cells with TP201565 despite prolonged growth with drug may be due to the fact that cells containing the NAMPTD93del were not present in the original flask used for inducing resistance to TP201565.
Similar(54)
Tumour management attempts to limit cancer growth, metastasis, and reduce the probability of obtaining resistance mutations through, for example, micro-environmental modification, or competition with non-resistant cancer cell populations or with healthy cells.
For several years it has been studied how to obtain resistance reduction by means of air injection under the hull.
It is known that by conventional ion beam and plasma treatments, the polymer samples can obtain resistance to chemical attacks; in addition, there is an increase in surface hardness, and a metal oxide layer is formed on the surface [5].
Whether cells escaping from these stresses inherit or obtain resistance abilities is unknown.
Kinoshita et al (2001) reported that cancer cells might obtain resistance to apoptosis once they have survived hypoxia.
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