Sentence examples for obtained potency from inspiring English sources

Obtained potency values were comparable in both assays (Table  1).

For 10 compounds, we obtained potency and selectivity data for the inhibition of expression of all three different trinucleotide repeat genes, ATN1, ATXN-3, and HTT (Table 1).

For agonist-stimulated [35S]GTPγS binding, data were analyzed with GraphPad Prism 4.0 software using nonlinear regression and sigmoidal curve fitting to obtain potency (EC50) and efficacy (Emax) values.

Curves were constructed and analyzed by fitting sigmoidal dose-response curves using the GraphPad Prism 4 program (GraphPad Prism Software Inc) to obtain potency (EC50, concentration of the ligand to give half-maximal effect) and efficacy (Emax⁡, % maximal stimulation over basal activity) values.

These analogues were designed to interact directly, or through a water-mediated hydrogen bond, with the C-terminal carboxylate group to obtain potency gains as observed for the previously reported pyrazole sulfonamide series.[ 8, 9] Crystal structure analysis of 44 in complex with LmNMT confirmed that this interaction was achieved.

Both the obtained estrogenic potencies and the contribution of each analyte (WWTP1) are presented in Figures 3(a) and 3(b), respectively.

Novel zinc binding groups (ZBGs) represent a novel strategy to obtain optimal potency and selectivity for zinc metalloproteases inhibitors.

The introduction of an unsaturated linking group between the terminal aryl ring and the amide moiety was the key to obtain good potency.

The BMR is then divided by the human-equivalent POD to obtain a potency estimate, under the assumption that risks extrapolate linearly with doses below the BMR.

The U.S. EPA Office of Research and Development has been at the forefront of risk assessment and cancer-evaluation methodology development for many years and it is an important resource for obtaining cancer potency data for specific chemicals determined to be human carcinogens.

At present, we do not have strong evidence to explain the discrepancy between the concentrations evaluated by ELISA and the order of potency obtained in the scratch assay for PRFext and PRFexu.