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Only two patients, both with SCLE, obtained a sustained remission after withdrawing medication.
A meta-analysis showed that only about 17% of patients with chronic hepatitis C obtained a sustained virological response on interferon monotherapy, which was the only recommended treatment until the late 1990 [ 7].
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We obtain a sustained performance for this ready-for-physics code that is a large fraction of peak.
A mix of polymers, PLGA, PEG-PLGA and PEG-PCL, were used to obtain a sustained drug delivery.
The developed strategy appears to be a very interesting tool to obtain a sustained release system for oligonucleotides with an efficient cellular delivery.
In the present work, the unstable LD LA was entrapped into biodegradable poly(lactic-co-glycolic acid) (PLGA) microspheres designed as depot systems to protect this prodrug against degradation and to obtain a sustained release of the intact compound.
According to the operating principle of MSSICG, we can theoretically obtain a sustained and steady acceleration which is sufficient to push the projectile to high speed by means of continuously increasing the series of driving coils and matching with the appropriate trigger strategy.
IFN therapy could not obtain a sustained virologic response 8 years before LT.
Different strategies are employed to obtain a sustained effect from these analgesics, for example sustained release oral dosage forms [2], [3], sustained release transdermal patches [4] and implanted infusion pumps [5].
Promotion of antiviral use in hospitalized patients may need to be repeated in order to obtain a sustained effect and to prevent further decrease in use.
Mice were treated with 0.1 mL of vehicle or nilotinib (75 mg/kg) by oral gavage daily for 6 d to obtain a sustained inhibition of MAPKs.
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