Sentence examples for obtain specificity from inspiring English sources

This has been a major limitation to lentiviral introduction of exogenous transgenes, which either quickly become silenced or are not truly expressed in a cell-specific manner, despite numerous attempts to obtain specificity [29 31].

A variety of experimental techniques have been developed to elucidate the peptide specificity for many modular signaling domains and obtain specificity profiles (e.g., the so-called Position-Specific Scoring Matrices, PSSMs), as a quantitative measure of the preference of each kinase domain for each amino acid residue at every peptide substrate position.

HuR does not act in isolation and interplay of HuR with other proteins and miRNAs is necessary to obtain specificity of interaction with these mRNAs.

The score ranges from 0 to 7 points, and the cut-off was set at 6 points to obtain specificity >85%.

To achieve sensitivity with such few reads, we started with the set of TIC alignments with an overhang of 8 nt, and used a clustering method to to obtain specificity.

This strategy is employed nationally in the U.S. and in global HIV surveillance efforts to enhance recall and obtain specificity in recent sexual behaviors of populations most at risk for HIV [ 20].

The obtained specificity was 82.65 and sensitivity was 83.63.

The obtained specificity for proteoliposomes is subsequently discussed in the context of the two "initial receptor models" and the evolutionary development of the chloroplast translocon.

The majority of kinase inhibitors target the ATP-binding site which, due to the conserved nature of this site among kinases, often leads to difficulties obtaining specificity [ 11].

Positive or negative ionization methods were tested and compared to obtain good specificity and sensitivity for yakuchinone A and IS determination.

Therefore, sensitive laboratory methods are needed to obtain sufficient specificity and sensitivity.