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The very first step in a site investigation program is to obtain published information relevant to the project.
"They did that and they found problems severe enough that warranted suspending all clinical research". Regarding the asthma experiment, federal investigators determined that researchers, as well as a Johns Hopkins review board that approved the research, failed to obtain published information about the drug Roche took and its effect on lung functioning.
A literature review was conducted to obtain published material on the definition and treatment of AE-IPF.
Additionally, the web-based search engine Google Scholar was used to obtain published literature related to maternal fee exemptions.
Medline, Embase, PsycINFO and Cochrane Database of Systematic Reviews (CDSR), clinical trial registries and pharmaceutical databases up to December 2013 were used to obtain published and unpublished data.
Based on these findings, normative data may have limited relevance to a clinical environment unless the same measurement methods used to obtain published data are also used in the clinical setting where they are applied.
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Among other things, university officials began the study before they had obtained published toxicity information on hexamethonium that was "readily available via routine MEDLINE and internet database searches".
For some taxa (Stylommatophora, Amphibolidae, Ellobiidae, Opisthobranchia and Littorinidae) we obtained published sequences from Genbank).
For demonstration, we obtained published lung cancer gene expression microarrays (Garber et al., 2001).
We obtained published Health Survey for England (HSE) data for BMI from the National Health Service NHS Information Centrere.
We searched and obtained published and unpublished data from 142 surveys of 24 h urinary sodium and 103 of dietary sodium conducted between 1980 and 2010 across 66 countries.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com