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We thought it would be useful to obtain overview methylation maps, albeit at reduced resolution, to understand the pattern of methylation at the genome-wide level.
In addition, the correlations (Pearson's R) between all input parameters and output metrics included in the analysis were evaluated to obtain overview of the model system.
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To obtain overviews of the dataset the data was first Z-score normalized along the columns and then either randomly subsampled or K-means down sampled.
However, there is a clear gain of using a common metamodel for all state variables in terms of obtaining overview of the input-output relationships as well as covariance patterns between the state variables.
Interactive graphs (http://www.ggobi.org) and motion chart (http://www.gapminder.org) services available on the Internet are used for obtaining overviews of large data sets.
To obtain an overview of the morphology and measure particle size of EV samples, isolated EVs were prepared for SEM analysis.
Molecular beam mass spectrometry was employed to obtain an overview of stable species and hydrocarbon intermediates.
Optical microscopy was employed to obtain an overview about the microstructure of the Ti coatings and to determine their porosity.
The CCLE data is also visualized within a Jupyter Notebook where specific tissues are explored in more depth, and K-means down-sampling is implemented to obtain an overview of the entire dataset (Supplementary Fig. 3b).
Principal components analysis was applied to obtain an overview of the sample variations and to identify behavioural patterns.
To obtain an overview of the expression pattern of OsPYL members in different tissues, quantitative RT-PCR was performed.
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