Sentence examples for obtain more efficacious from inspiring English sources

Compounds 13e, 13i, 13k, 14a, 14c, 14i, and 14k exhibited significant minimum inhibition concentrations, when compared with first line drugs isoniazid (INH) and rifampicin (RIF) and could be ideally suited for further modifications to obtain more efficacious compounds in the fight against multi-drug resistant tuberculosis.

Through in vivo real-time visualization and imaging quantification of biological targets of interest, a better understanding of the biological processes underlining the initiation and progression of diseases can be obtained for more efficacious diagnosis and treatment.

For the tβ3C-receptors, the EC50 value for CGP12177 (−9.66) is within the range of KD values obtained from antagonism of the more efficacious agonists (−9.11 to −9.94) suggesting that CGP12177 is a typical partial agonist causing its stimulation and antagonism by occupying the same conformation of the receptor (which is also the same conformation occupied by the other agonists).

More efficacious therapeutics may be obtained by selectively inhibiting the silencing pathway initiated by the relevant oncoprotein.

"We can now get stem cell lines that are more efficacious and heartier," he says.

Surprisingly, the lower efficacy agonist APO was the more efficacious positive reinforcer.

This included: discovery of human leukocyte antigen matching and its importance in minimization of graft-vs-host disease (GVHD [4], and the discovery that hematopoietic stem cells (HSC) could be more easily obtained from peripheral blood (and subsequently cord blood) to provide less invasive and more efficacious transplant procedures[5].

For example, the price of medication impacts on its efficacy, with more expensive medications being more efficacious than cheaper ones.

These results suggest that the protective efficacy of 0.1 mg WNIG was similar to that obtained with 0.5 mg of IVIG-IL, i.e. WNIG was at least 5-fold more efficacious.

A series of novel conjugates of brefeldin A (11a−c, 12a−c and 13a−c) were obtained by introducing a variety of nitrogen mustards at 4-OH or 7-OH position to explore more efficacious and less toxic antitumor agents.

Equivalent efficacy results were obtained for FA and a blend of FA and PA, whereas the commercial product Amasil (blend of FA and SF) was slightly more efficacious than Luprocid (blend of FA and PA) in compound mash feed.