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Hence, the failure of S. aureus to induce TLR-mediated NF-κB activation in pbMEC is not due to just obstructing the interaction of relevant PAMPs with TLRs (TLR2 in particular) through FCS.
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For instance, obstructing the interaction between HIF-1α and the co-activator CBP/p300 led to attenuation of HIF-induced gene expression and inhibition of tumour growth in a xenograft model [ 42].
Necrotic tissue was found obstructing the lumen of the esophagus.
After careful analysis, it became apparent that crystallographic contacts obstructed the key interaction driving the observed SAR, namely, formation of a salt bridge between Arg82 and the anionic substituent of this class of inhibitors.
Stein accused the judge of obstructing the Keystone State voters.
Surprisingly, instead of obstructing the MLN4924-induced growth suppression, P27 silencing enhanced its cytotoxicity.
These interactions are crucial for post-transcriptional regulation of target gene expression by obstructing the mRNA translation or stability in the cytoplasm, and depend on both the expression levels of miRNAs and target mRNAs [ 2, 3].
The influence of tubes obstructing the fluid flow is also accounted for.
E6 interactions with O 6 -methylguanine DNA methyltransferase and XRCC1 O 6 -methylguaninety of these proteins to repair the DNAages incurred, giving rise to genomethyltransferasen cells infected with HPV.
One of the offences is for obstructing the highway.
In Chinese medicine, the primary syndrome type of AECOPD is phlegm-heat obstructing the lungs [ 6].
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