Sentence examples for obstructing the interaction from inspiring English sources

For instance, obstructing the interaction between HIF-1α and the co-activator CBP/p300 led to attenuation of HIF-induced gene expression and inhibition of tumour growth in a xenograft model [ 42].

Hence, the failure of S. aureus to induce TLR-mediated NF-κB activation in pbMEC is not due to just obstructing the interaction of relevant PAMPs with TLRs (TLR2 in particular) through FCS.

After careful analysis, it became apparent that crystallographic contacts obstructed the key interaction driving the observed SAR, namely, formation of a salt bridge between Arg82 and the anionic substituent of this class of inhibitors.

These interactions are crucial for post-transcriptional regulation of target gene expression by obstructing the mRNA translation or stability in the cytoplasm, and depend on both the expression levels of miRNAs and target mRNAs [ 2, 3].

This interaction, which apparently involves the GLUT1 C-terminal region [27], may lead to a structural change obstructing the glucose-permeable pore while facilitating dehydroascorbate influx [30].

"The Palestinian leadership holds Israel responsible for obstructing the negotiations".

The Germans are obstructing the move towards common bank supervision.

Necrotic tissue was found obstructing the lumen of the esophagus.

There is no object obstructing the TX and RX antennas.

Bradykinin-mediated angioedema commonly affects the lips and tongue, potentially obstructing the oropharyngeal pathway, whereas the nasal passage is unlikely to be obstructed.

μ-Conotoxin (μ-CTX) inhibits Na+ flux by obstructing the Na+ channel pore.