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Some vital members of this pathway are simply not present in these cells, obviously obstructing activation of the entire pathway.
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Indeed, recent work suggests the primary role for Cyc8 Tup1 involves obstructing the activation domains of the DNA binding proteins responsible for its targeted recruitment [23].
Necrotic tissue was found obstructing the lumen of the esophagus.
Obstructing lesions of the oropharynx or esophagus may preclude passage of a standard echoendoscope.
One patient had an ulcerating oropharyngeal and glottic mass and obstructing disease of the transverse colon.
Debris and flooding also impeded and obstructed of parts of the Bruce, Gillies, and Palmerston highways.
Therefore, a major mechanism in the dimerization-induced activation of plexin appears to be the outward shift of the activation segment, which opens the otherwise obstructed active site to allow Rap binding and catalysis of GTP hydrolysis.
Microembolic particles produced by increased clotting activity may obstruct the microcirculation of the brain.
All of these abnormalities can obstruct the transmission of the ERG light stimulus into the eye.
Facebook defended its activation of the safety check feature.
The activation of the E.U.-I.M.F.
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CEO of Professional Science Editing for Scientists @ prosciediting.com