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Kermekchiev and colleagues suggested that the I707L mutation in KlenTaq1 could obstruct the transition between open and closed conformations because of its location near the mobile O helix, thereby slowing the enzyme.
As in the case of E47K, while the free-energy analysis suggests a destabilizing effect, interaction with nearby histidine residues could obstruct the transition of HA to the fusogenic state when the virus is endocytosed, in this way increasing the stability of HA.
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Many said they had concluded that much of the secular opposition was primarily interested in obstructing the transition to democracy at all costs, to try to block the Islamists from winning elections.
Ennahda condemned the assassination as a "cowardly" act "targeting the revolution and national unity, and obstructing the democratic transition process".
Overexpression of PTEN obstructed the epithelial mesenchymal transition (EMT) process in the primitive streak.
Ni-Cu alloy shows great ability to obstruct the diffusion of carbon in the transition zone during the welding of cast iron due to the low solubility of carbon in nickel alloy.
The nomination of John McCain, however, could obstruct this transition.
Will I obstruct the landscape?
No posts obstruct the fans' view.
He says Labour will obstruct the government.
Unfortunately, these structures obstruct the natural flow of a river.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com